Research News @ Gerstner Sloan-Kettering Graduate School of Biomedical Sciences

Researchers Learn How Signaling Molecule Orchestrates Breast Cancer's Spread

Thu, 03 Apr 2008 12:05:00 GMT

NEW YORK, April 3, 2008 - A study led by researchers at Memorial Sloan-Kettering Cancer Center has uncovered how breast tumors use a particular type of molecule to promote metastasis - the spread of cancer cells.

Therapeutic Cloning Treats Parkinson's Disease in Mice

Sun, 23 Mar 2008 14:20:00 GMT

NEW YORK, March 23, 2008 - Research led by investigators at Memorial Sloan-Kettering Cancer Center has shown that therapeutic cloning, also known as somatic-cell nuclear transfer (SCNT), can be used to treat Parkinson's disease in mice.

Researchers Identify New Genetic Marker for Breast Cancer

Mon, 03 Mar 2008 17:05:00 GMT

NEW YORK, March 3, 2008 - An international group of investigators led by scientists at Memorial Sloan-Kettering Cancer Center and the National Cancer Institute has identified a new genetic marker of risk for breast cancer.

Novel Mechanism Found That May Boost Impaired Function of Leukemia Protein

Sat, 01 Mar 2008 09:00:00 GMT

NEW YORK, February 29, 2008 - A new study led by researchers at Memorial Sloan-Kettering Cancer Center Reports on a novel mechanism that can enhance the function of a protein that is frequently impaired in patients with acute forms of leukemia.

Memorial Sloan-Kettering Team Creates Muscle Cells from Embryonic Stem Cells

Fri, 29 Jun 2007 00:00:00 GMT

Center News, July 2007 - A team of Memorial Sloan-Kettering investigators has reported for the first time a novel strategy to coax human embryonic stem cells (HESCs) to develop into cells that could potentially be used to repair the musculoskeletal system, including bone, cartilage, and muscle.

Harnessing the Immune System to Help the Body Fight Cancer

Sat, 28 Apr 2007 00:00:00 GMT

Center News, April 2007 - Memorial Sloan-Kettering Cancer Center clinicians and researchers have been at the forefront of developing new ways to guide the body's immune system toward producing a response that targets and destroys cancer cells.

Core Facilities Offer Centralized, Specialized Expertise and State-of-the-Art Equipment

Sat, 28 Apr 2007 00:00:00 GMT

Center News, April 2007 - To facilitate and enhance the work of Center researchers, Memorial Sloan-Kettering Cancer Center maintains a system of core facilities -- specialized laboratories and data centers that offer shared services to multiple users.

Joan Massagué Wins Passano Prize

Sat, 28 Apr 2007 00:00:00 GMT

Center News, April 2007 - Joan Massagué is the recipient of the 2007 Passano Award for the originality and importance of his work elucidating the mechanism of action for transforming growth factor-beta (TGF-b) signaling.

Johanna Joyce Named to Geoffrey Beene Chair

Sat, 28 Apr 2007 00:00:00 GMT

Center News, April 2007 - Johanna Joyce, of the Sloan-Kettering Institute's Cancer Biology and Genetics Program, has been named the first incumbent of a Geoffrey Beene Junior Faculty Chair.

Evidence Suggests Mad2 Gene May Help Initiate Cancer

Fri, 02 Mar 2007 00:00:00 GMT

Center News, February 2007 - A team of scientists led by Memorial Sloan-Kettering Cancer Center cancer biologist Robert Benezra has revealed new insights into the mechanism of tumor formation by boosting levels of the Mad2 gene in mice.

Alexandra Joyner Joins Memorial Sloan-Kettering Cancer Center

Fri, 02 Mar 2007 00:00:00 GMT

Center News, February 2007 - Alexandra Leigh Joyner has been appointed a Member in the Developmental Biology Program in the Sloan-Kettering Institute. She has also been named the incumbent of the Courtney Steel Chair in Pediatric Cancer Research.

Novel Regulation of the Common Tumor Suppressor PTEN

Fri, 02 Mar 2007 00:00:00 GMT

NEW YORK, January 12, 2007 -Researchers led by scientists at Memorial Sloan-Kettering Cancer Center have now identified fundamentally novel regulatory mechanisms of PTEN function. The findings from two related studies are published in the January 12 issue of Cell.

New Online Search Tool Helps Scientists Explore Genes in Medical Literature

Fri, 02 Mar 2007 00:00:00 GMT

NEW YORK, December 7, 2006 - Computational biology researchers today announced a new Internet tool for the exploration of the scientific literature in medicine and biology. The freely accessible iHOP service provides fast, accurate, comprehensive, and up-to-date summary information on more than 80,000 biological molecules by automatically extracting key sentences from millions of PubMed documents when a search is requested.

Spotlight on Young Faculty

Fri, 02 Mar 2007 00:00:00 GMT

Center News, February 2007 - Many of Memorial Sloan-Kettering's advances in patient care, research, and education are made by young staff members who are just beginning their careers.

Joan Massagué Elected to Institute of Medicine

Fri, 01 Dec 2006 00:00:00 GMT

Joan Massagué, Chair of the Cancer Biology and Genetics Program in the Sloan-Kettering Institute, has been elected a member of the Institute of Medicine.

When Biology Meets Structure

Fri, 01 Dec 2006 00:00:00 GMT

A collaboration driven by Jayakrishnan Nandakumar, a fifth-year graduate student in the Tri-Institutional Training Program in Chemical Biology, and guided by Sloan-Kettering Institute researchers Christopher Lima and Stewart Shuman, has led to the exquisite visualization of RNA ligase 2 (Rnl2).

T Cell Precursors Improve Immune Response After Bone Marrow Transplantation

Fri, 01 Dec 2006 00:00:00 GMT

A study led by immunologist and Adult Bone Marrow Transplant Service Chief Marcel R. van den Brink has demonstrated a novel strategy for boosting numbers of infection-fighting T cells in mice after allogeneic bone marrow transplantation.

Newly Approved Cancer Drug Based on 30 Years of Research

Fri, 01 Dec 2006 00:00:00 GMT

A drug developed at Memorial Sloan-Kettering and Columbia University has won approval from the US FDA. Vorinostat (Zolinza™) -- also known by its chemical name suberoylanilide hydroxamic acid (SAHA) -- was approved in October for the treatment of cutaneous T cell lymphoma (CTCL), a form of non-Hodgkin's lymphoma.

An Interview with Alan Hall

Fri, 01 Dec 2006 00:00:00 GMT

Alan Hall, Chair of the Sloan-Kettering Institute's Cell Biology Program, discusses his professional journey and explains his research objectives and program goals at Sloan-Kettering Institute.